Plant compound found in spices, herbs increases brain connections
Flavonoid apigenin has potential to treat diseases like schizophrenia, depression, Alzheimer’s and Parkinson’s
Date:
December 10, 2015
Source:
D’Or Institute for Research and Education
Summary:
Apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells, new lab research demonstrates.
FULL STORY
The neurons treated with apigenin (right) show more formation of synapses (red) than the neurons that were not treated.
Credit: Rehen et al.
Brazilian researchers from D’Or Institute for Research and Education (IDOR), Federal University of Rio de Janeiro (UFRJ) and Federal University of Bahia (UFBA) have demonstrated in laboratory that apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells.
Previous experiments with animals had already shown that substances from the same chemical group as the apigenin, known as flavonoids, positively affect memory and learning. Many studies highlight the potential of flavonoids to preserve and enhance brain function. While the effectiveness of flavonoids for brain health is not an entirely new concept, this research is the first to show the positive effects of apigegin directly on human cells and the first to unraveling its mechanism.
The scientists observed that just by applying apigenin to human stem cells in a dish they become neurons after 25 days — an effect they would not see without the substance. Moreover, the neurons that were formed made stronger and sophisticated connections among themselves after being treated with this natural compound.
“Strong connections between neurons are crucial for good brain function, memory consolidation and learning,” says neuroscientist from IDOR and UFRJ Stevens Rehen, leader author of the paper published in Advances in Regenerative Biology.
The research team conducted by Rehen demonstrated that apigenin works by binding to estrogen receptors, which affect the development, maturation, function, and plasticity of the nervous system. This group of hormones is known to delay the onset of psychiatric and neurodegenerative disorders such as schizophrenia, depression, Alzheimer’s and Parkinson’s disease. However, the use of estrogen-based therapies is limited by the increased risk of estrogen-dependent tumors and cardiovascular problems.
Researchers believe apigenin can be used as an alternative approach on future treatments for neurodegenerative diseases as well as in neuronal differentiation strategies in laboratory.
“We show a new path for new studies with this substance,” points out Rehen. “Moreover, flavonoids are present at high amounts in some foods and we can speculate that a diet rich in flavonoids may influence the formation of neurons and the way they communicate within the brain.”
Cleide S. Souza, Bruna S. Paulsen, Sylvie Devalle, Silvia Lima Costa, Helena L. Borges, Stevens K. Rehen. Commitment of human pluripotent stem cells to a neural lineage is induced by the pro-estrogenic flavonoid apigenin. Advances in Regenerative Biology, 2015; 2 (0) DOI: 10.3402/arb.v2.29244
D’Or Institute for Research and Education. “Plant compound found in spices, herbs increases brain connections: Flavonoid apigenin has potential to treat diseases like schizophrenia, depression, Alzheimer’s and Parkinson’s.” ScienceDaily. ScienceDaily, 10 December 2015. <www.sciencedaily.com/releases/2015/12/151210144912.htm>.
New detergent ponds have become a danger to children who have been eating them. The pods when consumed are poisonous and parents are warned to keep them out of the reach of children.
The family of Paul Bales tells us today he’s recovering and resting after doctors partially amputated his left leg, which was infected with the flesh-eating bacteria.
Wednesday evening, Mike Bales told 13WMAZ that his father, Paul Bales (see slideshow) was out of surgery and in stable condition after his left leg was amputated below the knee.
He said his dad lives on Lake Sinclair near Milledgeville and injured his leg when he slipped and fell on his dock May 2.
Paul Bales bandaged the cut and went golfing the next day but started feeling pain in his leg.
He was admitted to the Oconee Regional Medical Center on May 5, then sent to the Medical Center of Central Georgia a week later.
Mike Bales says doctors have told the family that his father suffers from necrotizing fasciitis, the same flesh-eating bacteria that struck north Georgia student Aimee Copeland and at least two other Georgians.
“He’s gotten to be stable, but they can’t get the infection from his leg,” he said.
The left leg had to be amputated because the bacteria damaged blood vessels in his leg, Mike Bales said.
After the surgery, he told us that doctors found more infected tissue in his father’s leg and will have to operate again. Â He said they could remove more of the leg.
Medical Center spokeswoman Janie Poulnott said Paul Bales is in stable condition but would not comment further.
The rising tide of Autism
By Craig Stellpflug,Â
(NaturalNews) Autism was once thought to be a psychological disorder because of the lack of eye contact that is hallmark in the child with autism. But autism cannot be treated and cured with psycho-therapy or psychotropic drugs. Autism is not a medical disorder that can be diagnosed with an X-ray or MRI and then cured with drugs or surgery. A lack of drugs is not the cause of autism! On the contrary, too much pharmaceutical intervention has been implicated as one of the multifactorial causes of…
Birth defects – could Epilim be the new Thalidomide?
By D Holt,Â
(NaturalNews) After the scandal of Thalidomide, it was said that important lessons were learned, and that it should never happen again. Now it comes to light that another set of drugs are causing birth defects, and have been since the seventies. Thalidomide was a “calming” drug used in the fifties to treat morning sickness, and led to birth deformities such as shortened or missing limbs, impaired hearing and eyesight, and internal injuries. This resulted in claims which cost millions of dollars…
Researchers vindicate omega-3 fatty acids in the prevention of inflammatory chronic diseases
By John Phillip,Â
(NaturalNews) Systemic inflammation is a primary factor in the development and progression of many chronic conditions ranging from heart disease and stroke to diabetes, dementia, and cancer. Most people have no idea that their risk of these conditions is dramatically increased, as disease-causing chemical messengers are continually released throughout the body as a result of low level inflammation. These messengers or cytokines can be life-saving in the case of a cut or burn, but when released as…
By Danna Norek,Â
(NaturalNews) Depression and anxiety remain two of the most pervasive mental health issues in American culture today. We currently have more medications than we’ve ever had to treat these conditions along with more natural, gentler alternatives like 5-HTP, St. John’s Wort, and others. Yet it seems both depression and anxiety have ballooned over the past several decades for reasons that can only be speculated upon. 5-HTP is a natural alternative to anti-anxiety medications. It can also be useful…
Resveratrol may be the missing link to prevent and even treat Alzheimer’s disease
By John Phillip,Â
(NaturalNews) Incidence of Alzheimer’s disease cases continue to explode at an unprecedented rate as processed food diets, overweight and obesity become the norm for middle and senior aged adults in the US and most western societies. By the year 2050, it’s projected that 13.2 million adults will suffer from this degenerative disease that ranks as the sixth leading cause of death, with many suffering early signs of the condition at earlier ages. Any natural compound that can be shown to prevent or…
Medicinal herb ginger helps protect against the effect of chemical parabens
By Celeste M. Smucker, MPH, PhD,Â
(NaturalNews) Traditional healers often use ginger to treat ailments ranging from nausea to arthritis pain. Recent studies highlight another use for ginger, the amelioration of the impact of parabens, a chemical widely used in the food and beverage industry and as a preservative in personal care products, drugs, and cosmetics. Parabens have been in the news recently thanks to studies which show the vast majority of Americans show signs of exposure. If ginger does indeed reduce parabens’ impact that…
Another Great Reason to Throw Out That Dry Cat Food
Recently researchers at the University of California-Davis published the results of a very interesting study that provides additional evidence of the importance of high moisture content in feline diets.
A recent study conducted at the University of California-Davis concludes that cats eat less, lose weight and maintain healthy body composition when fed wet diets.
Not only that, but wet (canned) cat food does not contain the massive amounts of fiber found in many dry cat food formulas. Fiber has been shown to interfere with the digestibility of other nutrients in cat food – and kitties aren’t even designed to process fiber and grain.
The UC-Davis researchers also concluded that cats much prefer canned food to either freeze-dried or dry food.
If you have a cat who is still eating dry food, you can find tools here at Mercola Healthy Pets to take you step-by-step through the transition to a species-appropriate diet. And if your cat needs to lose weight, you’ll find information on safe dieting for kitties as well.
Just as people are living longer lives, so are many pets.
In fact, pet owners with an elderly dog or cat around the house these days tend to brag about it!
Improved living conditions, treating companion animals as real members of the family and advances in veterinary care are major contributing factors to the longevity of pets nowadays.
Pets are living longer these days thanks to improved living situations and advances in veterinary care.
Two things that haven’t added to the longevity of dogs and cats are commercial pet foods and yearly re-vaccinations.
Tips for helping your pet live a long, healthy life include feeding a species-appropriate diet, refusing unnecessary vaccinations, insuring your dog or cat doesn’t become overweight, keeping your pet’s frame and organs in top condition, and arranging for regular vet checkups.
Deepak Chopra’s Lecture on The Mystery of Consciousness. Video produced by Alan Steinfeld and http://www.NewRealities.com This is Deepak’s opening lecture to his Seduction of Spirit retreat. One of the Chopra Center programs http://www.chopra.com where in 5 days participants learn the secrets of meditation, unlock the stillness that rests within your soul, and connect to their inner essence. Deepak’s new book is called The Ultimate Happiness Prescription.
ALL 3 of the FLESH EATING BACTERIA infections originated in the ATLANTA, GA area NEAR THE CDC!
LOCATION: (CDC) Centers for Disease Control and Prevention
1600 Clifton Rd. Atlanta, Georgia 30333, USA
LOCATION Case #1 May 1, 2012: 51 miles West of the CDC
LOCATION Case #2 May 7, 2012: 1.1 mile South of the CDC
LOCATION Case #3 May 4, 2012: 44.7 miles Northwest of the CDC
Case #1: Aimee Copeland, 24, was riding a homemade zip line near the Little Tallapoosa River near Carollton, Georgia May 1st when the line snapped, causing a gash in her left calf. The bacteria thought to have triggered the infection, Aeromonas hydrophila, thrives in warm climates and fresh (brackish) water, like the river where Copeland was kayaking and zip lining with friends. abcnews.go.com]
Case #2: Lana Kuykendall, 36, was infected on May 7th after she gave birth to twins at Emory University Hospital in Atlanta (Emory University Hospital Midtown in Atlanta – 201 Dowman Drive. Atlanta, Georgia 30322) www.myfoxatlanta.com
Case #3: Bobby Vaughn, 32, Cartersville, Georgia a Cartersville landscaper was injured at work May 4th when he fell from a tree and suffered a cut to his side. www.foxnews.com
[In accordance with Title 17 U.S.C. Section 107, this material is distributed without profit, for research and/or educational purposes. This constitutes ‘FAIR USE’ of any such copyrighted material.]
The Hidden Trigger to Alzheimer’s and Parkinson’s That 75% of People Carry
By Dr. Mercola
I strongly encourage you to watch the new documentary film Mercury Undercover, which exposes just how far those in power will go to prevent you from learning the truth about mercury contamination from dental amalgam—all in the name of money.
Dental amalgam is a primitive, pre-Civil War product that is 50 percent mercury, still commonly used in dental fillings.
Half of all North American dentists still use amalgam for its quick and easy profits, then pass the bill for damages on to the rest of us—damages to health, as well as to the environment.
Mercury Undercover discusses the mountain of evidence about mercury contamination, as reported by doctors, scientists, environmental experts and mercury-poisoned survivors.
The disturbing issues brought to light in this film will make you think twice before ordering a “catch-of-the-day” or planning your next dental procedure.
American dentistry’s 150-year affair with mercury is a tale profits first, people last.
Ancient Herb Proven to be a Potential Cure for Alzheimer’s
By Dr. Mercola
Ashwagandha is a small evergreen perennial herb that grows up to nearly 5 feet tall.
Common names used for ashwagandha include: Winter Cherry, Withania somnifera (Latin botanical name), and Indian Ginseng to name a few.
Regardless of the name you use to describe this adaptogenic herb, ashwaganda has been a part of India’s Ayurvedic medical system for thousands of years.
There it’s regarded as a wonder herb.
While often regarded as an herb for stress reduction and improved energy and vitality, there is a robust body of scientific research confirming ashwaganda’s potential therapeutic value in several dozen health conditions.
Now, new research has revealed this herb may also fight off the devastating effects of Alzheimer’s disease….
Is medicinal herb kratom a safe and effective alternative for treating pain, anxiety and depression?
By Jonathan Benson,
(NaturalNews) Mitragyna speciosa, also known as “kratom,” is a plant native to the rainforests of Southeast Asia that has long been used in traditional herbal medicine to treat pain, boost energy, alleviate anxiety and depression symptoms, and promote feelings of wellness and happiness. But because the plant allegedly exhibits opioid-like activity, the U.S. Drug Enforcement Administration (DEA) has placed it on its infamous Drugs and Chemicals of Concern list, which indicates that the agency may…
IASTM – The new wave in injury resolution without surgery
By Dr. Daniel Zagst,
(NaturalNews) Chiropractors and physical therapists must stay on the cutting edge with the latest techniques in rehabilitation and natural enhancement to achieve the best results for their patients. Instrument Assisted Soft Tissue Mobilization (IASTM) is a procedure that is rapidly growing in popularity due to its effectiveness and efficiency while remaining non-invasive. For those who are struggling with a chronic injury or want to bounce back from a recent injury without having to go the surgical…
Are veterinarians really over vaccinating? Recently, claims of a class action lawsuit surfaced accusing veterinarians of vaccinating pets that don’t need it.
The Law Firm of Childress Duffy Goldblatt, Ltd. of Chicago, Illinois, is investigating the pursuit of a class action lawsuit arising from the misrepresentation of the need for pet vaccinations. The investigation claims that every year over 30 thousand dogs and cats in the U.S. die from adverse reactions from unnecessary vaccines.
Are vaccines needed?
Over 10 years ago, some research was conducted that questioned the immunity resulting from vaccines and whether annual vaccinations should be required. There have not been any conclusions in this research. However, during this time, most veterinary schools in the U. S. have recommended a reduction in the number and frequency of required vaccination.
Some veterinarians believe that annual re-vaccination is an important and critical part of preventative health care. Others suggest that there is little scientific information to suggest that annual re-vaccination of older dogs is necessary for some diseases. There is insufficient information regarding the duration of immunity beyond a year. Of course, some vaccines (rabies) are required by law…..
Hunted for horns worth more than gold, South Africa’s rhinos face worst year on record
Conservationists are fighting a battle against poachers in South Africa – almost 2 rhinos a day are being killed for their lucrative horns. NBC’s Rohit Kachroo reports from the Kar-eeka reserve where veterinarians try to save a rhino which has been savagely wounded.
By Rohit Kachroo, NBC News
More than one rhino is being killed in South Africa by poachers each day — with 2012 on target to be the worst year on record.
Some 159 rhinos have fallen victim to poachers since January, a death toll that looks set to surpass last year’s grim figure of 449. In 2007, only 13 were killed in the country.
Demand comes from parts of China and Vietnam, where new wealth has combined with an age-old myth that rhino horns can be used to cure cancer.
Rhino horns are now worth an estimated $25,000 per pound, making their natural weapon worth more than gold…..
LOUISE HAY-101 POWERFULL THOUGTHS FOR LIFE-Louise Hay (born October 8, 1926) is an American motivational author, and the founder of Hay House, a publishing company. She has authored several New Thought self-help books, and is best known for her 1984 book, You Can Heal Your Life.
Biography
Hay recounted her life story in an interview with Mark Oppenheimer of the New York Times in May 2008.[1] In it Hay stated that she was born in Los Angeles to a poor mother who remarried Louise’s violent stepfather. She recounted that when she was about 5, she was raped by a neighbor. At 15 she dropped out of high school without a diploma, became pregnant and, on her 16th birthday, gave up her newborn baby girl to be adopted. She then recalled she moved to Chicago, where she worked in low paying jobs. In 1950 she moved on again to New York. She explained that at this point she changed her name and began a career as a fashion model. She was successful at this, working for Bill Blass, Oleg Cassini and Pauline Trigère. In 1954 she married the English businessman Andrew Hay, but went on to tell how, after 14 years of marriage, she was devastated when he left her for another woman.[1]
Hay said that about this time she found the First Church of Religious Science on 48th Street, that taught her the trans formative power of thought. Hay revealed that here she studied the New Thought works of authors like Florence Scovel Shinn, who claimed that positive thinking could change people’s material circumstances, and the Religious Science founder Ernest Holmes, who taught that the body could be healed through positive thinking.[citation needed]
By Hay’s account in the early 1970s she became a Religious Science practitioner. In this role she led people in spoken affirmations, which she believes will cure their illnesses, and became popular as a workshop leader. She also recalled how she had studied Transcendental Meditation with the Maharishi Mahesh Yogi at the Maharishi International University in Fairfield, Iowa.[2]
Hay described how in 1977 or 1978 she found she had cervical cancer, and how she came to the conclusion that by holding on to her resentment for her childhood abuse and rape she had contributed to its onset. She reported how she had refused conventional medical treatment, and began a regime of forgiveness, coupled with therapy, nutrition, reflexology and occasional enemas. She claimed in the interview that she rid herself of the cancer by this method, but declared that there is no doctor left alive who can confirm this story, while swearing to its truth.[1]
In 1976, Hay wrote her first book Heal Your Body, which began as a small pamphlet, containing a list of different bodily ailments and their “probable” metaphysical causes.[1] This pamphlet was later enlarged and extended into her book You Can Heal Your Life, published in 1984 [3][broken citation] As of February 2008, it was second on the New York Times miscellaneous paperback best sellers list.[4]
Around the same time she began leading support groups for people living with H.I.V. or AIDS which she called “Hay Rides”.[1] These grew from a few people in her living room to hundreds of men in a large hall in West Hollywood. Her work with AIDS patients drew fame and she was invited to appear on “The Oprah Winfrey Show” and “Donahue” in the same week, in March 1988. Following this, You Can Heal Your Life immediately landed on the New York Times best-seller list. More than 35 million copies are now in print around the world in over 30 languages [1][5] and it also has been made into a movie.[6] You Can Heal Your Life is also included in the book 50 Self-Help Classics[7] for being significant in its field. Some of these statistics are open to question however. Louise Hays writes on page 225 of her book (December 2000 printing) that the book has “. . . sold more than three million copies”. Given this disparity, it is more likely that the 35 million copies named in the subsequent 2007 and 2008 newspaper interviews should be 3.5 million.
Study finds the time of day can increase the risk of dying from sudden cardiac death
By J. D. Heyes,
(NaturalNews) So far, no one has been able to accurately predict the day, month and year we’ll depart this earth, but scientists have at least been able to narrow down the time of day when it’s most likely. Sort of. In a new study published in the research journal Nature, scientists have found that you’re more at risk of “sudden cardiac death” in the morning, with your risk rising again in the evening. Here’s why. The body works on a 24-hour clock, which is called the Circadian rhythm. Essentially…
Researchers at the National Institutes of Health have discovered how exposure to arsenic can turn normal stem cells into cancer stem cells and spur tumor growth. Inorganic arsenic, which affects the drinking water of millions of people worldwide, has been previously shown to be a human carcinogen. A growing body of evidence suggests that cancer is a stem-cell based disease. Normal stem cells are essential to normal tissue regeneration, and to the stability of organisms and processes. But cancer stem cells are thought to be the driving force for the formation, growth, and spread of tumors.
Michael Waalkes, Ph.D., and his team at the National Toxicology Program Laboratory, National Institute of Environmental Health Sciences, part of NIH, had shown previously that normal cells become cancerous when they are treated with inorganic arsenic. This new study shows that when these cancer cells are placed near, but not in contact with normal stem cells, the normal stem cells very rapidly acquire the characteristics of cancer stem cells. It demonstrates that malignant cells are able to send molecular signals through a semi-permeable membrane, where cells can’t normally pass, and turn the normal stem cells into cancer stem cells.
[In accordance with Title 17 U.S.C. Section 107, this material is distributed without profit, for research and/or educational purposes. This constitutes ‘FAIR USE’ of any such copyrighted material.]
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