Tag Archive: Parkinson’s


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Plant compound found in spices, herbs increases brain connections

Flavonoid apigenin has potential to treat diseases like schizophrenia, depression, Alzheimer’s and Parkinson’s

Date:
December 10, 2015
Source:
D’Or Institute for Research and Education
Summary:
Apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells, new lab research demonstrates.
FULL STORY

The neurons treated with apigenin (right) show more formation of synapses (red) than the neurons that were not treated.
Credit: Rehen et al.

Brazilian researchers from D’Or Institute for Research and Education (IDOR), Federal University of Rio de Janeiro (UFRJ) and Federal University of Bahia (UFBA) have demonstrated in laboratory that apigenin, a substance found in parsley, thyme, chamomile and red pepper, improves neuron formation and strengthens the connections between brain cells.

Previous experiments with animals had already shown that substances from the same chemical group as the apigenin, known as flavonoids, positively affect memory and learning. Many studies highlight the potential of flavonoids to preserve and enhance brain function. While the effectiveness of flavonoids for brain health is not an entirely new concept, this research is the first to show the positive effects of apigegin directly on human cells and the first to unraveling its mechanism.

The scientists observed that just by applying apigenin to human stem cells in a dish they become neurons after 25 days — an effect they would not see without the substance. Moreover, the neurons that were formed made stronger and sophisticated connections among themselves after being treated with this natural compound.

“Strong connections between neurons are crucial for good brain function, memory consolidation and learning,” says neuroscientist from IDOR and UFRJ Stevens Rehen, leader author of the paper published in Advances in Regenerative Biology.

The research team conducted by Rehen demonstrated that apigenin works by binding to estrogen receptors, which affect the development, maturation, function, and plasticity of the nervous system. This group of hormones is known to delay the onset of psychiatric and neurodegenerative disorders such as schizophrenia, depression, Alzheimer’s and Parkinson’s disease. However, the use of estrogen-based therapies is limited by the increased risk of estrogen-dependent tumors and cardiovascular problems.

Researchers believe apigenin can be used as an alternative approach on future treatments for neurodegenerative diseases as well as in neuronal differentiation strategies in laboratory.

“We show a new path for new studies with this substance,” points out Rehen. “Moreover, flavonoids are present at high amounts in some foods and we can speculate that a diet rich in flavonoids may influence the formation of neurons and the way they communicate within the brain.”


Story Source:

The above post is reprinted from materials provided by D’Or Institute for Research and Education. Note: Materials may be edited for content and length.


Journal Reference:

  1. Cleide S. Souza, Bruna S. Paulsen, Sylvie Devalle, Silvia Lima Costa, Helena L. Borges, Stevens K. Rehen. Commitment of human pluripotent stem cells to a neural lineage is induced by the pro-estrogenic flavonoid apigenin. Advances in Regenerative Biology, 2015; 2 (0) DOI: 10.3402/arb.v2.29244

Cite This Page:

D’Or Institute for Research and Education. “Plant compound found in spices, herbs increases brain connections: Flavonoid apigenin has potential to treat diseases like schizophrenia, depression, Alzheimer’s and Parkinson’s.” ScienceDaily. ScienceDaily, 10 December 2015. <www.sciencedaily.com/releases/2015/12/151210144912.htm>.

Prevent Disease

9 Essential Mood, Memory, and Cognitive Enhancers That Boost Brain Energy Metabolism

Mood-stabilizing drugs are purely antimanic agents, which are mainly for treating mania. However, natural mood stabilizers help the body metabolize brain chemicals which enhance mood, something drugs can never do due to specific metabolic pathways necessary to metabolize the chemical constituents. These ingredients not only improve mood, memory and cognition, but they do it without long-term side effects associated with medication. Here are 9 essential ingredients to look for in any supplement designed to boost your brain.

 

 

Just like any fine, multi-functional computer, your brain requires all its elements to perform correctly and fluidly. It is entirely electro-chemical in nature, and scientists are increasingly leaning to the conclusion that the roots of many psychiatric illnesses and mental health problems might be found in brain dysfunction. This just makes sense: a tiny piece of code can mess up a fine computer, but with the right code reinstalled, the computer resumes normal operation. The same can be said of the brain, its need for proper nutrition, and the concept of feeding the brain what it most needs, in order to restore and maintain the brain in its best possible condition.

Encouraging evidence exists for the use of omega-3 fatty acids, SAM-e, Kava Kava, R-Alpha Lipoic Acid, GABA, and l-tryptophan to enhance response within the brain.

Investigators are examining children with ADHD (attention deficit/hyperactivity disorder) and adults with bipolar disorder and depression, along with a variety of other psychiatric conditions and types of cognitive impairments. Conditions such as Parkinson’s, Alzheimer’s, ALS (Lou Gehrig’s disease), MS (multiple sclerosis), MD (muscular dystrophy), all inhibit cell function and hinder the brain’s responsiveness to stimuli.

Brain energy metabolism is very important to normal brain function, so it’s no surprise to find that this factor is reduced in Alzheimer’s victims and other dementia patients: the greater the loss of energy, the more severe the dementia.

Ensuring optimal intake of key nutrients such as vitamins and antioxidants throughout one’s lifetime may be an important wellness strategy to help prevent brain diseases and prevent the decline in our cognitive abilities. Approximately 6-8% of all persons aged 65+ have developed Alzheimer’s disease, and the prevalence of this disease is increasing. The current research lends further support to the use of antioxidants and a vitamin enriched daily dietary supplement program to help support the brain function as we age.

9 Essential Mood, Memory, and Cognitive Enhancers That Boost Brain Energy Metabolism

1. ACETYL-L-CARNITINE:
In a 2010 Tokyo study, the aged rats were supplemented with Acetyl-L-Carnitine to determine its effects on memory, learning capacity, and brain synaptic functions. For 3 months, 344 rats were given Acetyl-L-Carnitine (100 mg/kg bodyweight). At the end of the study, the scientsists concluded that Acetyl-L-Carnitine increases synaptic neurotransmission in the brain and consequently improves learning capacity in aging rats.

2. R-ALPHA LIPOIC ACID (R-ALA):
R-ALA reduces cataract formation, and reduces oxidative stress in the heart muscle while raising levels in the heart and liver. It also lowers glucose levels by increasing insulin metabolism and decreases numbness in Diabetics, increases energy levels within the brain cells, can decrease LDL cholesterol and remove protein oxidation for a healthy heart, and inhibits free radicals more effectively than vitamin E.

3. L-THREONINE:
Threonine is an essential amino acid and not synthesized by humans. Threonine supports cardiovascular, liver, central nervous, and immune system function. Threonine combines with the amino acids aspartic acid and methionine to help liver digest fats and fatty acids. L-threonine has been tried for ALS because, like BCAAs, it affects glutamate metabolism. Open trials and one double-blind study have shown some short-term improvement in symptoms. The research also demonstrated that symptoms of Multiple Sclerosis (MS), another disease that affects nerve and muscle, are alleviated with threonine treatment. Threonine is an immunostimulant, which promotes the growth of thymus gland.

4. L-TYROSINE:
L-Tyrosine has been proposed as a treatment for various conditions in which mental function is impaired or slowed down, such as fatigue and depression. It has also been tried for attention deficit disorder (ADD). Preliminary evidence, including small, double-blind trials, suggests that tyrosine supplements may help fight fatigue and improve memory and mental function in people who are deprived of sleep or exposed to other forms of stress.

5. PANTOTHENIC ACID:
Pantothenic acid is used in the manufacture of hormones, red blood cells, and acetylcholine, an important neurotransmitter (a signal carrier between nerve cells).

6. CO ENZYME-Q-10:
C0-Q-10” prevents oxidation of the cell membrane and mitochondria within the cell, thereby preserving youthful neurological function, and protecting the capillaries from becoming fragile; it also enhances cerebral oxygenation.

7. METHYLCOBALAMIN:
The neurologically-active form of vitamin B-12, Methylcobalamin is effective in slowing the progression of untreatable diseases and neurological aging. Japan’s scientific literature reveals 334 published studies on methylcobalamin; the studies consider the treatment beneficial for any neurological disease. For example, in patients with MS their cynocobalamin is destroyed, and methylcobalamin attempts to reverse this process.

8. DIMETHYLGLYCINE (DMG):
DMG is a dietary supplement which supports the immune, circulatory, and cardiovascular systems. It is useful for controlling epileptic seizures, and for improving neurological functions, as well as muscle recovery and endurance. DMG is a nutrient that is found in the cells of both plants and animals. The human body produces DMG in very small amounts. Supplementing the diet with higher levels of DMG greatly improves the nutritional environment of the cell. DMG has been found effective in supporting immune system function and better utilization of oxygen at the cellular level.

9. GAMMA AMINO BUTYRIC ACID (GABA):
The ability of the limbic system and the rest of the brain to communicate in an orderly manner depends critically on inhibition. GABA inhibits the cells from firing, diminishing the anxiety-related messages from reaching the cortex. GABA, glutamine and glycine are vital for energy and the smooth running of the brain functions. B6 (pyridoxine) is GABA’s most important partner.


Life Choice Neurotransmitter Support contains all 9 of the above ingredients which is why it’s one of the best formulas available in the natural healthy industry. If you’re not familiar with Life Choice, discover why few supplement brands compare in terms of quality, purity and effectiveness.

  • This formulation is a vast improvement over any other for its bioavailability with added the patented Sigma-Tau’s Acetyl-L-Carnitine with advanced delivery, complete with clinical studies showing the effectiveness of this material opposed to other forms of Acetyl-L-Carnitine.
  • Instead of using DL-Alpha Lipoic Acid, instead the Life Choice Neurotransmitter Support uses R-Alpha Lipoic acid. This formulation matches the same two principle ingredients used in the clinical Study of Berkley School of Medicine and from that stage Life Choice created an even more advanced delivery with the unknown amino acid L-Threonine, not to be confused with L-Theonine.
  • Through research and investigation, Life Choice have further advanced the relationships between neurological biochemistry and bioavailability for an ingestible supplement.

This isn’t just any natural health supplement. Neurotransmitter Support’s precision formulation acts to improve brain energy metabolism, and with it, brain function. It’s one of the most advanced formulas I’ve seen on the market that synergistically uses this 9 ingredients to effectively change the way the brain responds to the body and its environment.

Sources:
psych.med.nyu.edu
life-choice.net
science.gov
elavtoit.com

Dave Mihalovic
is a Naturopathic Doctor who specializes in vaccine research, cancer prevention and a natural approach to treatment.

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Health

 

The Hidden Trigger to Alzheimer’s and Parkinson’s That 75% of People Carry

 

By Dr. Mercola

 

I strongly encourage you to watch the new documentary film Mercury Undercover, which exposes just how far those in power will go to prevent you from learning the truth about mercury contamination from dental amalgam—all in the name of money.

Dental amalgam is a primitive, pre-Civil War product that is 50 percent mercury, still commonly used in dental fillings.

Half of all North American dentists still use amalgam for its quick and easy profits, then pass the bill for damages on to the rest of us—damages to health, as well as to the environment.

Mercury Undercover discusses the mountain of evidence about mercury contamination, as reported by doctors, scientists, environmental experts and mercury-poisoned survivors.

The disturbing issues brought to light in this film will make you think twice before ordering a “catch-of-the-day” or planning your next dental procedure.

American dentistry’s 150-year affair with mercury is a tale profits first, people last.

 

Read Full Article Here

 

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Holistic Health

 

Ancient Herb Proven to be a Potential Cure for Alzheimer’s

 

By Dr. Mercola

 

Ashwagandha is a small evergreen perennial herb that grows up to nearly 5 feet tall.

Common names used for ashwagandha include: Winter Cherry, Withania somnifera (Latin botanical name), and Indian Ginseng to name a few.

Regardless of the name you use to describe this adaptogenic herb, ashwaganda has been a part of India’s Ayurvedic medical system for thousands of years.

There it’s regarded as a wonder herb.

While often regarded as an herb for stress reduction and improved energy and vitality, there is a robust body of scientific research confirming ashwaganda’s potential therapeutic value in several dozen health conditions.

Now, new research has revealed this herb may also fight off the devastating effects of Alzheimer’s disease….

 

Read Full Article Here

 

 

Is medicinal herb kratom a safe and effective alternative for treating pain, anxiety and depression?

 

By Jonathan Benson,

 

(NaturalNews) Mitragyna speciosa, also known as “kratom,” is a plant native to the rainforests of Southeast Asia that has long been used in traditional herbal medicine to treat pain, boost energy, alleviate anxiety and depression symptoms, and promote feelings of wellness and happiness. But because the plant allegedly exhibits opioid-like activity, the U.S. Drug Enforcement Administration (DEA) has placed it on its infamous Drugs and Chemicals of Concern list, which indicates that the agency may…

 

Read Full Article Here

 

 

 

IASTM – The new wave in injury resolution without surgery

 

By Dr. Daniel Zagst,

 

(NaturalNews) Chiropractors and physical therapists must stay on the cutting edge with the latest techniques in rehabilitation and natural enhancement to achieve the best results for their patients. Instrument Assisted Soft Tissue Mobilization (IASTM) is a procedure that is rapidly growing in popularity due to its effectiveness and efficiency while remaining non-invasive. For those who are struggling with a chronic injury or want to bounce back from a recent injury without having to go the surgical…

 

Read Full Article Here

 

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Pet Health

 

Are Veterinarians Over-vaccinating?

 

By: PetPlace Staff

 

Are veterinarians really over vaccinating? Recently, claims of a class action lawsuit surfaced accusing veterinarians of vaccinating pets that don’t need it.

The Law Firm of Childress Duffy Goldblatt, Ltd. of Chicago, Illinois, is investigating the pursuit of a class action lawsuit arising from the misrepresentation of the need for pet vaccinations. The investigation claims that every year over 30 thousand dogs and cats in the U.S. die from adverse reactions from unnecessary vaccines.

Are vaccines needed?

Over 10 years ago, some research was conducted that questioned the immunity resulting from vaccines and whether annual vaccinations should be required. There have not been any conclusions in this research. However, during this time, most veterinary schools in the U. S. have recommended a reduction in the number and frequency of required vaccination.

Some veterinarians believe that annual re-vaccination is an important and critical part of preventative health care. Others suggest that there is little scientific information to suggest that annual re-vaccination of older dogs is necessary for some diseases. There is insufficient information regarding the duration of immunity beyond a year. Of course, some vaccines (rabies) are required by law…..

 

Read Full Article Here

 

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Wildlife

 

Hunted for horns worth more than gold, South Africa’s rhinos face worst year on record

 

Conservationists are fighting a battle against poachers in South Africa – almost 2 rhinos a day are being killed for their lucrative horns. NBC’s Rohit Kachroo reports from the Kar-eeka reserve where veterinarians try to save a rhino which has been savagely wounded.
By Rohit Kachroo, NBC News

More than one rhino is being killed in South Africa by poachers each day — with 2012 on target to be the worst year on record.

Some 159 rhinos have fallen victim to poachers since January, a death toll that looks set to surpass last year’s grim figure of 449. In 2007, only 13 were killed in the country.

Demand comes from parts of China and Vietnam, where new wealth has combined with an age-old myth that rhino horns can be used to cure cancer.

Rhino horns are now worth an estimated $25,000 per pound, making their natural weapon worth more than gold…..

 

Read Full Article Here

 

 

 

http://www.msnbc.msn.com/id/32545640

 

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Positivity Mind and Body

LOUISE HAY-101 POWERFUL THOUGHTS FOR LIFE

 

Uploaded by 5461584 on Dec 9, 2011

 

LOUISE HAY-101 POWERFULL THOUGTHS FOR LIFE-Louise Hay (born October 8, 1926) is an American motivational author, and the founder of Hay House, a publishing company. She has authored several New Thought self-help books, and is best known for her 1984 book, You Can Heal Your Life.
Biography
Hay recounted her life story in an interview with Mark Oppenheimer of the New York Times in May 2008.[1] In it Hay stated that she was born in Los Angeles to a poor mother who remarried Louise’s violent stepfather. She recounted that when she was about 5, she was raped by a neighbor. At 15 she dropped out of high school without a diploma, became pregnant and, on her 16th birthday, gave up her newborn baby girl to be adopted. She then recalled she moved to Chicago, where she worked in low paying jobs. In 1950 she moved on again to New York. She explained that at this point she changed her name and began a career as a fashion model. She was successful at this, working for Bill Blass, Oleg Cassini and Pauline Trigère. In 1954 she married the English businessman Andrew Hay, but went on to tell how, after 14 years of marriage, she was devastated when he left her for another woman.[1]

Hay said that about this time she found the First Church of Religious Science on 48th Street, that taught her the trans formative power of thought. Hay revealed that here she studied the New Thought works of authors like Florence Scovel Shinn, who claimed that positive thinking could change people’s material circumstances, and the Religious Science founder Ernest Holmes, who taught that the body could be healed through positive thinking.[citation needed]

By Hay’s account in the early 1970s she became a Religious Science practitioner. In this role she led people in spoken affirmations, which she believes will cure their illnesses, and became popular as a workshop leader. She also recalled how she had studied Transcendental Meditation with the Maharishi Mahesh Yogi at the Maharishi International University in Fairfield, Iowa.[2]

Hay described how in 1977 or 1978 she found she had cervical cancer, and how she came to the conclusion that by holding on to her resentment for her childhood abuse and rape she had contributed to its onset. She reported how she had refused conventional medical treatment, and began a regime of forgiveness, coupled with therapy, nutrition, reflexology and occasional enemas. She claimed in the interview that she rid herself of the cancer by this method, but declared that there is no doctor left alive who can confirm this story, while swearing to its truth.[1]
In 1976, Hay wrote her first book Heal Your Body, which began as a small pamphlet, containing a list of different bodily ailments and their “probable” metaphysical causes.[1] This pamphlet was later enlarged and extended into her book You Can Heal Your Life, published in 1984 [3][broken citation] As of February 2008, it was second on the New York Times miscellaneous paperback best sellers list.[4]

Around the same time she began leading support groups for people living with H.I.V. or AIDS which she called “Hay Rides”.[1] These grew from a few people in her living room to hundreds of men in a large hall in West Hollywood. Her work with AIDS patients drew fame and she was invited to appear on “The Oprah Winfrey Show” and “Donahue” in the same week, in March 1988. Following this, You Can Heal Your Life immediately landed on the New York Times best-seller list. More than 35 million copies are now in print around the world in over 30 languages [1][5] and it also has been made into a movie.[6] You Can Heal Your Life is also included in the book 50 Self-Help Classics[7] for being significant in its field. Some of these statistics are open to question however. Louise Hays writes on page 225 of her book (December 2000 printing) that the book has “. . . sold more than three million copies”. Given this disparity, it is more likely that the 35 million copies named in the subsequent 2007 and 2008 newspaper interviews should be 3.5 million.

 

 

 

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Articles of Interest

 

Study finds the time of day can increase the risk of dying from sudden cardiac death

 

By J. D. Heyes,

 

(NaturalNews) So far, no one has been able to accurately predict the day, month and year we’ll depart this earth, but scientists have at least been able to narrow down the time of day when it’s most likely. Sort of. In a new study published in the research journal Nature, scientists have found that you’re more at risk of “sudden cardiac death” in the morning, with your risk rising again in the evening. Here’s why. The body works on a 24-hour clock, which is called the Circadian rhythm. Essentially…

 

Read Full Article Here

 

 

 

Arsenic Turns Stem Cells Cancerous, Spurring Tumor Growth

 

Researchers at the National Institutes of Health have discovered how exposure to arsenic can turn normal stem cells into cancer stem cells and spur tumor growth. Inorganic arsenic, which affects the drinking water of millions of people worldwide, has been previously shown to be a human carcinogen. A growing body of evidence suggests that cancer is a stem-cell based disease. Normal stem cells are essential to normal tissue regeneration, and to the stability of organisms and processes. But cancer stem cells are thought to be the driving force for the formation, growth, and spread of tumors.

Michael Waalkes, Ph.D., and his team at the National Toxicology Program Laboratory, National Institute of Environmental Health Sciences, part of NIH, had shown previously that normal cells become cancerous when they are treated with inorganic arsenic. This new study shows that when these cancer cells are placed near, but not in contact with normal stem cells, the normal stem cells very rapidly acquire the characteristics of cancer stem cells. It demonstrates that malignant cells are able to send molecular signals through a semi-permeable membrane, where cells can’t normally pass, and turn the normal stem cells into cancer stem cells.

 

Read Full Article Here

 

 

 

[In accordance with Title 17 U.S.C. Section 107, this material is distributed without profit, for research and/or educational purposes. This constitutes ‘FAIR USE’ of any such copyrighted material.]

Food Safety

 

Washington Consumers Advised Not to Eat a Local Farm’s Eggs

By News Desk

Eggs produced by Daizen Farms in Burlington, WA are from hens that ate feed contaminated with rodent droppings and Salmonella, according to the Washington State Department of Agriculture (WSDA).There have been no illnesses linked to the eggs, but WSDA is…

http://www.foodsafetynews.com/2012/03/washington-consumers-warned-not-to-eat-a-local-farms-eggs/?utm_source=newsletter&utm_medium=email&utm_campaign=120320

 

Pathogen Detection System Takes a Cue from Fireflies

By James Andrews

Biology researchers in the United Kingdom have developed a device that can detect foodborne pathogens using a variant of a simple, seemingly unlikely chemical: Firefly luciferase, the enzyme that makes fireflies’ abdomens light up.The device, called “Bioluminescent Assay in Real-Time”…

http://www.foodsafetynews.com/2012/03/pathogen-detection-system-takes-a-cue-from-fireflies/?utm_source=newsletter&utm_medium=email&utm_campaign=120321

 

House Budget Seeks Steep Spending Cuts

 

By Helena Bottemiller

Both the U.S. Food and Drug Administration and the U.S. Department of Agriculture’s Food Safety and Inspection service could face cuts under a new budget proposal put out by House Republicans on Tuesday.Though the budget outline, released by Budget Chairman…

http://www.foodsafetynews.com/2012/03/house-budget-seeks-steep-spending-cuts/?utm_source=newsletter&utm_medium=email&utm_campaign=120321

 

Health

 

Antibiotics Risky for E. Coli Patients, Study Confirms

 

By Gretchen Goetz

Among children with E. coli infections, those given antibiotics are more likely to develop a life-threatening complication called hemolytic uremic syndrome (HUS),
to a new study.Avoiding antibiotics as a treatment for E. coli has been a longstanding recommendation for…

http://www.foodsafetynews.com/2012/03/antibiotics-risky-for-e-coli-patients-study-confirms/?utm_source=newsletter&utm_medium=email&utm_campaign=120321

 

Holistic Health

 

17 Micrograms of This in Your Body Lowers Your IQ by 10 Points 17 Micrograms of This in Your Body Lowers Your IQ by 10 Points

 

How to flush it out – There is little doubt toxic heavy metals and chemicals in our environment contribute to the vast majority of cancers, MS, Parkinson’s and Alzheimer’s disease. Here’s a quick way to unclog these disease-causing and IQ-destroying elements from your body…

http://articles.mercola.com/sites/articles/archive/2012/03/21/dr-clement-on-detoxification.aspx?e_cid=20120321_DNL_art_1

 

Why You Need More of This Crucial Vitamin If You Are Heavy

 

Being overweight, obese or simply heavy with muscle affects the amount needed of this crucial nutrient to help you prevent disease and stay healthy.

Vitamin D is a fat-soluble, hormone-like vitamin, and many therefore believe that if you’re obese you need more of it because body fat acts as a “sink” by collecting it.

http://articles.mercola.com/sites/articles/archive/2012/03/21/vitamin-d-for-obese.aspx?e_cid=20120321_DNL_art_2

 

Pet Health

 

Help for Cats That Freak Out at the Vet’s Office

 

Sixty percent of cat owners say their cat hates vet visits. If your kitty despises trips to the vet, there are things you can do to help get him ready for his next appointment. And don’t be afraid to check out local offices to find a practice that excels at being cat-friendly.

http://healthypets.mercola.com/sites/healthypets/archive/2012/03/21/cats-hate-vet-visits.aspx

Recalls

 

Canada Beef Recall Includes More Than 135 Products

By News Desk

More than 135 products are part of the recall in Canada of frozen ground beef processed by the Saskatchewan-based New Food Classics, a plant that has filed for bankruptcy and ceased operations.The beef may be contaminated with E. coli O157:H7…

http://www.foodsafetynews.com/2012/03/canada-beef-recall-includes-more-than-135-products/?utm_source=newsletter&utm_medium=email&utm_campaign=120320